Can phenytoin cause anemia

WebPhenytoin, particularly in high dosages, may cause hyperglycemia by inhibiting insulin release. The drug may also raise serum glucose levels in diabetic patients. Therapy with phenytoin should be administered cautiously in patients with diabetes mellitus, glucose intolerance, or a predisposition to hyperglycemia. WebFeb 22, 2024 · Rarely, warfarin can cause the death of skin tissue (necrosis). This complication occurs within a few days of starting warfarin treatment. Seek immediate medical care if you notice sores, changes in skin color or temperature, or severe pain on your skin. Talk to your health care provider about these less serious side effects.

Phenytoin-induced aplastic anemia in generalized tonic …

Commonly reported side effects of phenytoin include: congenital anomalies. Other side effectsinclude: hepatic necrosis, ataxia, confusion, constipation, depression, dizziness, drowsiness, fatigue, hypertrichosis, mental status changes, myasthenia, nervousness, numbness, tremor, tremor of hands, vertigo, … See more Along with its needed effects, phenytoin may cause some unwanted effects. Although not all of these side effects may occur, if they do … See more Applies to phenytoin: compounding powder, injectable solution, oral capsule, oral capsule extended release, oral suspension, oral tablet chewable. See more Some side effects of phenytoin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your … See more Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. … See more Webepileptic patients, ASMs can cause anemia. Folic acid can be given to carbamazepine-treated anemic patients. There is growing evidence that it improves hemoglobin and leukocytes in individuals who take it. ... cases of aplastic anemia were described as well with phenytoin, valproate, and ethosuximide through interference with deoxyribonucleic ... incidence of smoking in usa https://ironsmithdesign.com

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WebJan 1, 2009 · Drug-induced immune hemolytic anemia (DIIHA) is rare. The incidence of drug-induced immune thrombocytopenia and neutropenia is quite well documented (10 to 18 and 2 to 15 cases per million, respectively), 1, – 3 but there are no good data for DIIHA. We have roughly estimated it to be around 1 in 1 million of the population, by comparing it to … WebApr 11, 2024 · The number of people living with chronic kidney disease (CKD) is growing as our global population continues to expand. With aging, diabetes, and cardiovascular disease being major harbingers of kidney disease, the number of people diagnosed with diabetic kidney disease (DKD) has grown concurrently. Poor clinical outcomes in DKD could be … WebSep 20, 2024 · Medications can cause vitamin deficiencies, including antibiotics, antacids, metformin (antidiabetic) and phenytoin (antiseizure). Tapeworm infections can lead to … inboard throttle control

Folate-deficiency anemia: MedlinePlus Medical Encyclopedia

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Can phenytoin cause anemia

Megaloblastic Anemia During Anticonvulsant Drug Therapy - JAMA

WebAntiepileptic drugs carbamazepine, phenytoin, and valproic acid induced aplastic anemia occurs via toxic metabolites. 11–13 The risk of aplastic anemia ranging from 1.4 to 60 cases/million, was detected among users of carbamazepine (within a 5-month period). 14 Felbamate proved to be a risk factor for aplastic anemia with an incidence of 127 ... WebApr 14, 2024 · Taking warfarin with phenytoin can increase the level of phenytoin in your body. This may lead to more side effects. Also, phenytoin can affect how the body …

Can phenytoin cause anemia

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WebNov 7, 2024 · Hair growth. Constipation. Increased blood sugar. Serious side effects of phenytoin are less common but may still occur. If you experience any of the following, or any other concerning side effects, seek medical attention immediately: Yellowing of the skin or eyes. Allergic reactions, such as rash, blisters, swelling of the mouth or face, tight ...

WebA 53-yr-old man sequentially developed aplastic anemia from phenytoin and carbamazepine. Both compounds undergo metabolism to potentially toxic arene oxide … WebSep 20, 2024 · Hemodialysis can also cause iron deficiency anemia. One study showed that patients receiving hemodialysis may lose up to 2 g of iron per year. Pregnancy can also cause iron stores to be low. During pregnancy, the body produces more red blood cells to support the developing fetus, which uses up the mother’s iron stores.

WebCauses of this type of anemia include: Too little folic acid in your diet; Hemolytic anemia; Long-term alcoholism; Use of certain medicines (such as phenytoin [Dilantin], methotrexate, sulfasalazine, triamterene, pyrimethamine, trimethoprim-sulfamethoxazole, and barbiturates) The following raise your risk for this type of anemia: Alcoholism WebPhenytoin also can cause anemia. Because it interferes with vitamin D metabolism, phenytoin can cause weakening of the bones (osteomalacia). Other important side …

WebThe nutrient-drug interaction between folate and phenytoin is a two-way interaction. Folate deficiency resulting from long-term phenytoin therapy is a common occurrence, but progression of the deficiency to a megaloblastic anemia is rare. However, there are data to suggest nonanemic folate deficiency may be detrimental to the patient.

WebUse of certain medicines (such as phenytoin [Dilantin], methotrexate, sulfasalazine, triamterene, pyrimethamine, trimethoprim-sulfamethoxazole, and barbiturates) ... Symptoms of anemia can cause discomfort. In pregnant women, folate deficiency has been associated with neural tube or spinal defects (such as spina bifida) ... inboard technology m1WebPhenytoin may cause swelling and bleeding of the gums. ... (including liver disease caused by past phenytoin use), lupus, folate or vitamin B-12 deficiency (megaloblastic anemia). ... inboard technology melectric skateboardWebMegaloblastic anaemia due to phenytoin sodium. Megaloblastic anaemia due to phenytoin sodium. Megaloblastic anaemia due to phenytoin sodium. Megaloblastic anaemia due … incidence of solitary kidneyWebAnemia can be caused by many conditions, including loss of blood during heavy menstruation, pregnancy, blood donation, bleeding ulcers, chronic heart failure, and surgery (before and after). There is also a type of anemia called anemia of chronic disease, which can occur in people with chronic kidney failure and those undergoing chemotherapy. inboard the gliderWebMegaloblastic anemia is a type of macrocytic anemia.An anemia is a red blood cell defect that can lead to an undersupply of oxygen. Megaloblastic anemia results from inhibition of DNA synthesis during red blood cell … incidence of speciesWebFeb 1, 2009 · As noted above, myeloproliferative disorders (sometimes called refractory anemia) are a more common cause of macrocytosis and anemia among older persons … incidence of sore throatWebJul 19, 2006 · AED use was more prevalent among cases (9.2%) than among controls (0.8%). After adjustment for confounders, the use of AEDs was significantly associated with aplastic anemia (adjusted odds ratio (OR), 9.5; 95% confidence interval (CI), 3.0–39.7). The most frequently used AEDs were carbamazepine (CBZ), valproic acid (VPA), and … inboard toilet layout