The promise and peril of chemical probes
WebbThe most powerful discovery app ever built for researchers! WebbChemical probes offer a biological rather than a clinical validation of the target. The Target 2035 initiative, an open-science alliance of international biomedical scientists, has set an …
The promise and peril of chemical probes
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WebbDOI. 10.1038/nchembio.1867. Type. Journal article. Journal. Nat Chem Biol. Publication Date. 08/2015. Volume. 11. Pages. 536 - 541 Webb21 mars 2024 · Scilit is currently under system maintenance from 28th February 2024 until 12th March 2024, during this time it will be unavailable to update the databases.
WebbRegulator. We provide tools both resourcing to help regulators sets standards and best practices, provide regulatory support functions, and educate on U.S. state-based insurance statute. what you shoud do if you have a loss, and the Wisconsin Insurance Plan. WebbChemical probes are powerful reagents with increasing impacts on biomedical research. However, probes of poor quality or that are used incorrectly generate misleading results. …
WebbChemical probes are selective modulators that are used in cell assays to link a phenotype to a gene and have become indispensable tools to explore gene function and discover therapeutic targets. Chemical probe off-targets are a confounding factor as the observed phenotype may be driven by inhibition of an unknown off-target instead of the targeted … WebbChemical probes are powerful reagents with increasing impacts on biomedical research. However, probes of poor quality or that are used incorrectly generate misleading results. …
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